The mechanism by which hypercholesterolemia is generated is well clarified, and is a mutation in the gene that regulates the concentration of LDL cholesterol in the liver.
In fact, the cholesterol that circulates in the blood is produced, for the most part, by the liver to guarantee all the important functions of our body. Normally the liver can “feel” the concentration of cholesterol in the blood and produce the right amount.
If the regulatory gene is altered, the liver will not control cholesterol production, which will inevitably increase in the blood. This can cause serious health problems but can be treated with new drugs specific to the type of genetic alteration present in a patient.
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